Most of the time, coloboma is identified by the unusual shape of the iris, and an individual may not experience any issues with their vision or eyes at all. Coloboma can also be a part of another condition, such as fetal alcohol syndrome or CHARGE syndrome. It can happen unexpectedly with no real origin, or it can be passed on to children from parents through either recessive or dominant genes. However, it is possible to have more than one of these areas affected.Ĭases of coloboma can be completely isolated, which means it isn’t a feature in a more extensive condition. If the fissure doesn’t close near the front, the baby can have coloboma of the iris or lens, and if the fissure doesn’t close near the back, they can have coloboma of the optic nerve or retina. In rare cases, the optic fissure doesn’t completely close at the ends, resulting in coloboma of the eye. At five weeks in the womb, this optic fissure starts to close, starting at the center of the seam. Underneath these stalks, there’s a seam that runs from end to end named the optic fissure. Eventually, a major portion of these stalks becomes the optic nerves, and the ends of these stalks become the eyes. The eyes essentially grow from the brain, starting out as simple stalks. Developmentĭuring the fourth week of pregnancy, a baby’s eyes begin to develop.
According to the collection of studies, coloboma can affect 0.5 to 2.2 people out of every 10,000. It’s a fairly rare condition, and most studies can’t seem to agree just how rare because there could be numerous individuals that haven’t been diagnosed. The word is derived from the Greek word “koloboma,” which means “curtailed” or “defect.” It is a defect of the eye that is actually developed in the womb, so an individual would have the condition for their entire life. If a person has coloboma of the eyelid, part of the eyelid may be absent, and if they have coloboma of the iris, they may have irregularly shaped pupils. ConditionĮssentially, the term coloboma is used to describe the condition where a portion of tissue is completely missing from the eye or eyelid. Here, we discuss what coloboma is, how it’s developed, how it can affect the eye, and what kind of treatment or observation is recommended.
The eye disorder can also affect the eyelids, but is more common in the eye itself.
These changes in appearance are attributed to coloboma, which can affect the lens, iris, retina, or optic nerve. There is one optical condition that can result in keyhole-shaped or cat-like pupils from birth. But, occasionally, we may notice something different about another’s pupils. Usually, iris color is what sets one pair of eyes apart from another. Bright blue irises can be mesmerizing, and hazel eyes can easily draw attention. So, when a pair of eyes have a unique or vivid feature, we immediately take note of it. We find eye contact important in daily conversation and human connection, and eyes have always fascinated human beings.
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